FireworksLearn more at: Adobe.com
I do websites. Fireworks is specifically built for web designers. That's why it's the best. Photoshop has more photographic-related features, plugins, effects, etc... but as far as ease-of-use goes, Fireworks is #1.
One of my favorite features is how integrated the environment is, allowing full vector graphic creation and raster image creation within the same window. The non-destructive effects and properties panels are intuitive and easy to use. Once you apply an effect, you can later edit the properties of that effect or remove it, without altering the original object. Fireworks does, however, say they can write your HTML for you... but avoid it if you can. Write your own. It'll be better for everyone.